test_locus_http Locus14789.htm ADDITIONAL_LINKS: key is UniGene Mm.35708 url = http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=35708 ---------------------------------------------- ---------------------------------------------- EXTERNAL_ANNOTATION: Not Available FUNCTION: Not Available GENBANK: AC002397 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3287367&db=Nucleotide&dopt=GenBank g AAC36012 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3287370&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=3287370&all=1 ---------------------------------------------- BC003726 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=13277629&db=Nucleotide&dopt=GenBank m AAH03726 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=13277630&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=13277630&all=1 ---------------------------------------------- BC016431 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=16741169&db=Nucleotide&dopt=GenBank m AAH16431 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=16741170&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=16741170&all=1 ---------------------------------------------- ---------------------------------------------- LOCUS: Not Available MAP: key is Chromosome 6 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?org=mouse&chr=6&query=Grcb&cmd=focus&fill=40&size=40 ---------------------------------------------- key is Cytogenetic 6 RefSeq ---------------------------------------------- key is Genetic 6 60.19 cM MGD url = http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:1315208 ---------------------------------------------- NOMENCLATURE: key is Grcb gene rich cluster, B gene ---------------------------------------------- key is LocusID 14789 ---------------------------------------------- OVERVIEW: key is Alternate Symbols B ---------------------------------------------- key is Locus Type gene with protein product, function known or inferred ---------------------------------------------- key is Product gene rich cluster, B gene ---------------------------------------------- REFSEQ: key is PROVISIONAL key is GenBank Source AC002397 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=AC002397&dopt=DocSum&dispmax=1000 ---------------------------------------------- key is Protein NP_038562 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305105&db=Protein&dopt=GenPept gene rich cluster, B gene BL url = /cgi-bin/Entrez/blink?pid=7305105&all=1 ---------------------------------------------- key is mRNA NM_013534 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305104&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is 1. ---------------------------------------------- key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Evidence supported by alignment with both mRNA and ESTs (6) ---------------------------------------------- key is Genomic Contig NT_002572 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NT_002572.2&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NT_002572.2&from=39181&to=55768&strand=1&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NT_002572.2&_gene=Grcb&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=mouse&MAPS=cntg,stsnw-r,rh,mgi,besnw,locnw,loc&chr=6&gnl=NT_002572.2&verbose=on&query=LOCUS(14789) ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=mouse&contig=NT_002572.2&gene=Grcb&lid=14789 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?org=mouse&cntg=cntg&contig=NT_002572.2&gene=Grcb&lid=14789 ---------------------------------------------- key is Protein NP_038562 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305105&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=7305105&all=1 ---------------------------------------------- key is mRNA NM_013534 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305104&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is 2. ---------------------------------------------- key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Evidence supported by alignment with mRNA ---------------------------------------------- key is Genomic Contig NW_000265 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NW_000265.1&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NW_000265.1&from=258786&to=275681&strand=2&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NW_000265.1&_gene=Grcb&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=mouse&MAPS=cntgnw,stsnw-r,rh,mgi,besnw,locnw&chr=6&gnl=NW_000265.1&verbose=on&query=LOCUS(14789) ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=mouse&contig=NW_000265.1&gene=Grcb&lid=14789 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?org=mouse&cntg=cntgnw&contig=NW_000265.1&gene=Grcb&lid=14789 ---------------------------------------------- key is Protein NP_038562 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305105&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=7305105&all=1 ---------------------------------------------- key is Strain C57BL/6J ---------------------------------------------- key is mRNA NM_013534 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7305104&db=Nucleotide&dopt=GenBank ---------------------------------------------- ---------------------------------------------- RELATIONSHIPS: key is Human Homology Maps NCBI vs. MGD 12q13 HSU47926 url = ./LocRpt.cgi?l=10536 Mm url = /Homology/view.cgi?map=ncbi_mgd&tax_id=10090&chr=6&symbol=Grcb Hs url = /Homology/view.cgi?map=ncbi_mgd&tax_id=9606&chr=12&symbol=HSU47926 ---------------------------------------------- UCSC vs. MGD 12q13 HSU47926 url = ./LocRpt.cgi?l=10536 Mm url = /Homology/view.cgi?map=ucsc_mgd&tax_id=10090&chr=6&symbol=Grcb Hs url = /Homology/view.cgi?map=ucsc_mgd&tax_id=9606&chr=12&symbol=HSU47926 ---------------------------------------------- ---------------------------------------------- Locus16590.htm ADDITIONAL_LINKS: key is UniGene Mm.4394 url = http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=4394 ---------------------------------------------- ---------------------------------------------- EXTERNAL_ANNOTATION: Not Available FUNCTION: key is GeneRIF Gene References into Function: ---------------------------------------------- 11964302 url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=11964302 Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis ---------------------------------------------- Gene Ontology url = http://www.geneontology.org/ ---------------------------------------------- key is TM ---------------------------------------------- membrane url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0016020 IEA MGD ---------------------------------------------- ATP binding url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005524 IEA MGD ---------------------------------------------- transferase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0016740 IEA MGD ---------------------------------------------- intracellular url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005622 IEA MGD ---------------------------------------------- protein kinase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0004672 IEA MGD ---------------------------------------------- protein tyrosine kinase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0004713 IEA MGD ---------------------------------------------- regulation of cell cycle url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0000074 IEA MGD ---------------------------------------------- integral membrane protein url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0016021 IEA MGD ---------------------------------------------- cell growth and/or maintenance url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0008151 IEA MGD ---------------------------------------------- protein amino acid phosphorylation url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0006468 IEA MGD ---------------------------------------------- transmembrane receptor protein tyrosine kinase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0004714 IEA MGD ---------------------------------------------- transmembrane receptor protein tyrosine kinase signaling pathway url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0007169 IEA MGD ---------------------------------------------- ---------------------------------------------- GENBANK: L11358 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=293325&db=Nucleotide&dopt=GenBank g AAA37420 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=293326&db=Protein&dopt=GenPept BALB/c BL url = /cgi-bin/Entrez/blink?pid=293326&all=1 ---------------------------------------------- X65998 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50433&db=Nucleotide&dopt=GenBank g CAA46799 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50434&db=Protein&dopt=GenPept ICR BL url = /cgi-bin/Entrez/blink?pid=50434&all=1 ---------------------------------------------- CAA46800 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50435&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=50435&all=1 ---------------------------------------------- AW741410 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=7653185&db=Nucleotide&dopt=GenBank m ---------------------------------------------- X65997 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50431&db=Nucleotide&dopt=GenBank m CAA46798 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50432&db=Protein&dopt=GenPept ICR BL url = /cgi-bin/Entrez/blink?pid=50432&all=1 ---------------------------------------------- Y00864 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50423&db=Nucleotide&dopt=GenBank m CAA68772 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=50424&db=Protein&dopt=GenPept BALB/c BL url = /cgi-bin/Entrez/blink?pid=50424&all=1 ---------------------------------------------- ---------------------------------------------- LOCUS: Not Available MAP: key is Chromosome 5 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?org=mouse&chr=5&query=Kit&cmd=focus&fill=40&size=40 ---------------------------------------------- key is Cytogenetic 5 RefSeq ---------------------------------------------- key is Genetic 5 42.0 cM MGD url = http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:96677 ---------------------------------------------- key is Markers Chr. 5 3714 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=179184 ---------------------------------------------- Chr. 5 Y00864 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=179184 ---------------------------------------------- ---------------------------------------------- NOMENCLATURE: key is Kit kit oncogene ---------------------------------------------- key is LocusID 16590 ---------------------------------------------- OVERVIEW: key is Alias dominant spotting spotted sterile male Steel Factor Receptor Dominant white spotting c-kit proto-oncogene protein ---------------------------------------------- key is Alternate Symbols W, Bs, Fdc, Ssm, CD117, c-KIT, belly-spot ---------------------------------------------- key is Locus Type gene with protein product, function known or inferred ---------------------------------------------- key is Product c-kit ---------------------------------------------- key is RefSeqSummary The c-Kit proto-oncogene is the cellular homolog of the transforming gene of a feline retrovirus (v-Kit). The c-kit protein includes characteristics of a protein kinase transmembrane receptor. ---------------------------------------------- REFSEQ: key is REVIEWED key is Domains Immunoglobulin url = /Structure/cdd/cddsrv.cgi?uid=smart00409 score:125 ---------------------------------------------- Immunoglobulin domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00047 score:94 ---------------------------------------------- Protein kinase domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00069 score:198 ---------------------------------------------- Immunoglobulin C-2 Type url = /Structure/cdd/cddsrv.cgi?uid=smart00408 score:83 ---------------------------------------------- Tyrosine kinase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00219 score:610 ---------------------------------------------- Serine/Threonine protein kinases, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00220 score:159 ---------------------------------------------- ---------------------------------------------- key is GenBank Source AW741410,Y00864 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=AW741410,Y00864&dopt=DocSum&dispmax=1000 ---------------------------------------------- key is Protein NP_066922 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=10863917&db=Protein&dopt=GenPept c-kit BL url = /cgi-bin/Entrez/blink?pid=10863917&all=1 ---------------------------------------------- key is Strain BALB/c ---------------------------------------------- key is mRNA NM_021099 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=10947120&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Domains Immunoglobulin url = /Structure/cdd/cddsrv.cgi?uid=smart00409 score:125 ---------------------------------------------- Immunoglobulin domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00047 score:94 ---------------------------------------------- Protein kinase domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00069 score:402 ---------------------------------------------- Immunoglobulin C-2 Type url = /Structure/cdd/cddsrv.cgi?uid=smart00408 score:83 ---------------------------------------------- Tyrosine kinase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00219 score:616 ---------------------------------------------- Serine/Threonine protein kinases, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00220 score:308 ---------------------------------------------- ---------------------------------------------- key is Evidence supported by alignment with both mRNA and ESTs (51) ---------------------------------------------- key is Genomic Contig NW_000230 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NW_000230.1&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NW_000230.1&from=1594776&to=1676260&strand=1&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NW_000230.1&_gene=Kit&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=mouse&MAPS=cntgnw,stsnw-r,rh,mgi,besnw,locnw&chr=5&gnl=NW_000230.1&verbose=on&query=LOCUS(16590) ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=mouse&contig=NW_000230.1&gene=Kit&lid=16590 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?org=mouse&cntg=cntgnw&contig=NW_000230.1&gene=Kit&lid=16590 ---------------------------------------------- key is Model Protein XP_132123 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=20832868&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=20832868&all=1 ---------------------------------------------- key is Model mRNA XM_132123 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=20832867&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is Strain C57BL/6J ---------------------------------------------- ---------------------------------------------- RELATIONSHIPS: key is Human Homology Maps NCBI vs. MGD 4q11-q12 KIT url = ./LocRpt.cgi?l=3815 Mm url = /Homology/view.cgi?map=ncbi_mgd&tax_id=10090&chr=5&symbol=Kit Hs url = /Homology/view.cgi?map=ncbi_mgd&tax_id=9606&chr=4&symbol=KIT ---------------------------------------------- UCSC vs. MGD 4q11-q12 KIT url = ./LocRpt.cgi?l=3815 Mm url = /Homology/view.cgi?map=ucsc_mgd&tax_id=10090&chr=5&symbol=Kit Hs url = /Homology/view.cgi?map=ucsc_mgd&tax_id=9606&chr=4&symbol=KIT ---------------------------------------------- NCBI vs. EST-based RH Map 4q11-q12 X06182 url = ./LocRpt.cgi?l=16590 Mm url = /Homology/view.cgi?map=ncbi_est&tax_id=10090&chr=5&symbol=Y00864 Hs url = /Homology/view.cgi?map=ncbi_est&tax_id=9606&chr=4&symbol=X06182 ---------------------------------------------- UCSC vs. EST-based RH Map 4q11-q12 X06182 url = ./LocRpt.cgi?l=16590 Mm url = /Homology/view.cgi?map=ucsc_est&tax_id=10090&chr=5&symbol=Y00864 Hs url = /Homology/view.cgi?map=ucsc_est&tax_id=9606&chr=4&symbol=X06182 ---------------------------------------------- UCSC vs. Hudson et al. 4q11-q12 AW263947 url = ./LocRpt.cgi?l=16590 Mm url = /Homology/view.cgi?map=natgen_paper&tax_id=10090&chr=5&symbol=Y00864 Hs url = /Homology/view.cgi?map=natgen_paper&tax_id=9606&chr=4&symbol=AW263947 ---------------------------------------------- ---------------------------------------------- Locus2523.htm ADDITIONAL_LINKS: key is OMIM 211100 url = http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=211100 ---------------------------------------------- key is UniGene Hs.69747 url = http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=69747 ---------------------------------------------- GeneCards url = http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?FUT1 ---------------------------------------------- KEGG pathway: Blood group glycolipid biosynthesis - lact series url = http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00601 ---------------------------------------------- KEGG pathway: Blood group glycolipid biosynthesis - neolact series url = http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00602 ---------------------------------------------- Blood Group Antigen Gene Mutation Database url = http://www.bioc.aecom.yu.edu/bgmut/hh.htm ---------------------------------------------- ---------------------------------------------- EXTERNAL_ANNOTATION: Not Available FUNCTION: key is EC Number 2.4.1.69 url = http://www.expasy.ch/cgi-bin/nicezyme.pl?2.4.1.69 ---------------------------------------------- Gene Ontology url = http://www.geneontology.org/ ---------------------------------------------- key is Other Ontologies ---------------------------------------------- Golgi P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- Transferase E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- Integral membrane P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- Unspecified membrane P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- ---------------------------------------------- key is TM ---------------------------------------------- Golgi apparatus url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005794 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- membrane fraction url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005624 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- fucosyltransferase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0008417 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- blood group antigen url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005555 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- carbohydrate metabolism url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005975 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- integral plasma membrane protein url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005887 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=2118655 ---------------------------------------------- ---------------------------------------------- GENBANK: AB004859 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217920&db=Nucleotide&dopt=GenBank g BAA20556 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217921&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2217921&all=1 ---------------------------------------------- AB004860 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217922&db=Nucleotide&dopt=GenBank g BAA20557 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217923&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2217923&all=1 ---------------------------------------------- AB004861 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217924&db=Nucleotide&dopt=GenBank g BAA20558 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217925&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2217925&all=1 ---------------------------------------------- AB004862 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217926&db=Nucleotide&dopt=GenBank g BAA20559 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217927&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2217927&all=1 ---------------------------------------------- AB004863 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217928&db=Nucleotide&dopt=GenBank g BAA20560 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2217929&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2217929&all=1 ---------------------------------------------- Z69587 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=1616598&db=Nucleotide&dopt=GenBank g CAA93435 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=1648868&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=1648868&all=1 ---------------------------------------------- M35531 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=183887&db=Nucleotide&dopt=GenBank m AAA52639 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=306830&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=306830&all=1 ---------------------------------------------- ---------------------------------------------- LOCUS: Not Available MAP: key is Chromosome 19 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&chr=19&ovr=ideogr&maps=scan-r,est,loc&VERBOSE=ON&cmd=focus&fill=40&size=40&query=FUT1 ---------------------------------------------- key is Cytogenetic 19q13.3 HUGO url = http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:120618 ---------------------------------------------- key is Markers Chr. 19 G15901 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=37175 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=19&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=37175&ZOOM=10 ---------------------------------------------- Chr. - D19S596 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=42586 D19S596 ---------------------------------------------- Chr. 19 STS-M35531 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=53731 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=19&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=53731&ZOOM=10 ---------------------------------------------- Chr. 19 RH78937 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=64899 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=19&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=64899&ZOOM=10 ---------------------------------------------- Chr. 19 SHGC-35310 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=69684 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=19&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=69684&ZOOM=10 ---------------------------------------------- ---------------------------------------------- NOMENCLATURE: key is FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included) ---------------------------------------------- key is LocusID 2523 ---------------------------------------------- OVERVIEW: key is Alias Fucosyltransferase-1 (Bombay phenotype) fucosyltransferase 1 (alpha (1,2) fucosyltransferase, Bombay phenotype included) ---------------------------------------------- key is Alternate Symbols H, HH ---------------------------------------------- key is Locus Type gene with protein product, function known or inferred ---------------------------------------------- key is Product fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included) ---------------------------------------------- key is Proteome Summary Alpha(1,2)fucosyltransferase (alpha-2-fucosyltransferase, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase); forms the H blood-group antigen ---------------------------------------------- REFSEQ: key is PROVISIONAL key is Domains Glycosyl transferase family 11 url = /Structure/cdd/cddsrv.cgi?uid=pfam01531 score:1193 ---------------------------------------------- key is GenBank Source M35531 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=M35531&dopt=DocSum&dispmax=1000 ---------------------------------------------- key is Protein NP_000139 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4503805&db=Protein&dopt=GenPept fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included) BL url = /cgi-bin/Entrez/blink?pid=4503805&all=1 ---------------------------------------------- key is mRNA NM_000148 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4503804&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Evidence supported by alignment with mRNA ---------------------------------------------- key is Genomic Contig NT_033316 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NT_033316.1&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NT_033316.1&from=1601299&to=1605878&strand=1&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NT_033316.1&_gene=FUT1&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&MAPS=est,clone,loc,cntg-r&verbose=on&gnl=NT_033316.1&query=NT_033316.1&cmd=FOCUS ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=hs&contig=NT_033316.1&gene=FUT1&lid=2523 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?contig=NT_033316.1&gene=FUT1&lid=2523 ---------------------------------------------- key is Protein NP_000139 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4503805&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=4503805&all=1 ---------------------------------------------- key is mRNA NM_000148 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4503804&db=Nucleotide&dopt=GenBank ---------------------------------------------- ---------------------------------------------- RELATIONSHIPS: key is Mouse Homology Maps NCBI vs. MGD 7 23.20 cM Fut1 url = ./LocRpt.cgi?l=14343 Hs url = /Homology/view.cgi?map=ncbi_mgd&tax_id=9606&chr=19&symbol=FUT1 Mm url = /Homology/view.cgi?map=ncbi_mgd&tax_id=10090&chr=7&symbol=Fut1 ---------------------------------------------- UCSC vs. MGD 7 23.20 cM Fut1 url = ./LocRpt.cgi?l=14343 Hs url = /Homology/view.cgi?map=ucsc_mgd&tax_id=9606&chr=19&symbol=FUT1 Mm url = /Homology/view.cgi?map=ucsc_mgd&tax_id=10090&chr=7&symbol=Fut1 ---------------------------------------------- ---------------------------------------------- Locus5797.htm ADDITIONAL_LINKS: key is OMIM 176888 url = http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176888 ---------------------------------------------- key is UniGene Hs.154151 url = http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=154151 ---------------------------------------------- GeneCards url = http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?PTPRM ---------------------------------------------- ---------------------------------------------- EXTERNAL_ANNOTATION: Not Available FUNCTION: key is EC Number 3.1.3.48 url = http://www.expasy.ch/cgi-bin/nicezyme.pl?3.1.3.48 ---------------------------------------------- Gene Ontology url = http://www.geneontology.org/ ---------------------------------------------- key is Other Ontologies ---------------------------------------------- Hydrolase E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10809770 ---------------------------------------------- Integral membrane P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=1655529 ---------------------------------------------- Receptor (signalling) P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=1655529 ---------------------------------------------- ---------------------------------------------- key is TM ---------------------------------------------- protein dephosphorylation url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0006470 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10809770 ---------------------------------------------- integral plasma membrane protein url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005887 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=1655529 ---------------------------------------------- transmembrane receptor protein tyrosine phosphatase url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0005001 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10809770 ---------------------------------------------- ---------------------------------------------- GENBANK: AA281524 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=1924204&db=Nucleotide&dopt=GenBank m ---------------------------------------------- X58288 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=32455&db=Nucleotide&dopt=GenBank m CAA41226 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=32456&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=32456&all=1 ---------------------------------------------- ---------------------------------------------- LOCUS: Not Available MAP: key is Chromosome 18 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&chr=18&ovr=ideogr&maps=scan-r,est,loc&VERBOSE=ON&cmd=focus&fill=40&size=40&query=PTPRM ---------------------------------------------- key is Cytogenetic 18p11.2 HUGO url = http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:128093 ---------------------------------------------- key is Markers Chr. - G10607 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=2693 ---------------------------------------------- Chr. 18 WI-9017 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=29528 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=18&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=29528&ZOOM=10 ---------------------------------------------- Chr. 18 Cda09f01 url = http://www.ncbi.nlm.nih.gov/genome/sts/sts.cgi?uid=60128 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&CHR=18&MAPS=rh,wiyac,g3,gb4,shgcg3,marsh,thon,loc,comp,sts&sts=60128&ZOOM=10 ---------------------------------------------- ---------------------------------------------- NOMENCLATURE: key is LocusID 5797 ---------------------------------------------- key is PTPRM protein tyrosine phosphatase, receptor type, M ---------------------------------------------- OVERVIEW: key is Alias protein tyrosine phosphatase mu precursor protein tyrosine phosphatase, receptor type, mu polypeptide ---------------------------------------------- key is Alternate Symbols RPTPM, RPTPU, PTPRL1, HR-PTPU, R-PTP-MU ---------------------------------------------- key is Locus Type gene with protein product, function known or inferred ---------------------------------------------- key is Product protein tyrosine phosphatase, receptor type, M precursor ---------------------------------------------- key is Proteome Summary Receptor-type protein tyrosine phosphatase M ---------------------------------------------- key is RefSeqSummary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. ---------------------------------------------- REFSEQ: key is REVIEWED key is Domains MAM domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00629 score:406 ---------------------------------------------- Immunoglobulin url = /Structure/cdd/cddsrv.cgi?uid=smart00409 score:102 ---------------------------------------------- Fibronectin type 3 domain url = /Structure/cdd/cddsrv.cgi?uid=smart00060 score:101 ---------------------------------------------- Fibronectin type III domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00041 score:126 ---------------------------------------------- Protein-tyrosine phosphatase url = /Structure/cdd/cddsrv.cgi?uid=pfam00102 score:800 ---------------------------------------------- Dual specificity phosphatase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=pfam00782 score:86 ---------------------------------------------- Dual specificity phosphatase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00195 score:84 ---------------------------------------------- Protein tyrosine phosphatase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00194 score:857 ---------------------------------------------- Protein tyrosine phosphatase, catalytic domain motif url = /Structure/cdd/cddsrv.cgi?uid=smart00404 score:324 ---------------------------------------------- Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others) url = /Structure/cdd/cddsrv.cgi?uid=smart00137 score:436 ---------------------------------------------- ---------------------------------------------- key is GenBank Source AA281524,X58288 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=AA281524,X58288&dopt=DocSum&dispmax=1000 ---------------------------------------------- key is Protein NP_002836 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=18860904&db=Protein&dopt=GenPept protein tyrosine phosphatase, receptor type, M precursor BL url = /cgi-bin/Entrez/blink?pid=18860904&all=1 ---------------------------------------------- key is mRNA NM_002845 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=18860903&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Domains Protein-tyrosine phosphatase url = /Structure/cdd/cddsrv.cgi?uid=pfam00102 score:766 ---------------------------------------------- Dual specificity phosphatase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00195 score:84 ---------------------------------------------- Protein tyrosine phosphatase, catalytic domain url = /Structure/cdd/cddsrv.cgi?uid=smart00194 score:786 ---------------------------------------------- Protein tyrosine phosphatase, catalytic domain motif url = /Structure/cdd/cddsrv.cgi?uid=smart00404 score:310 ---------------------------------------------- ---------------------------------------------- key is Evidence supported by alignment with both mRNA and ESTs (15) ---------------------------------------------- key is Genomic Contig NT_030853 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NT_030853.3&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NT_030853.3&from=799980&to=910490&strand=2&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NT_030853.3&_gene=PTPRM&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&MAPS=est,clone,loc,cntg-r&verbose=on&gnl=NT_030853.3&query=NT_030853.3&cmd=FOCUS ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=hs&contig=NT_030853.3&gene=PTPRM&lid=5797 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?contig=NT_030853.3&gene=PTPRM&lid=5797 ---------------------------------------------- key is Model Protein XP_012741 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=17491416&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=17491416&all=1 ---------------------------------------------- key is Model mRNA XM_012741 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=20557738&db=Nucleotide&dopt=GenBank ---------------------------------------------- ---------------------------------------------- RELATIONSHIPS: key is Mouse Homology Maps NCBI vs. MGD 17 38.30 cM Ptprm url = ./LocRpt.cgi?l=19274 Hs url = /Homology/view.cgi?map=ncbi_mgd&tax_id=9606&chr=18&symbol=PTPRM Mm url = /Homology/view.cgi?map=ncbi_mgd&tax_id=10090&chr=17&symbol=Ptprm ---------------------------------------------- UCSC vs. MGD 17 38.30 cM Ptprm url = ./LocRpt.cgi?l=19274 Hs url = /Homology/view.cgi?map=ucsc_mgd&tax_id=9606&chr=18&symbol=PTPRM Mm url = /Homology/view.cgi?map=ucsc_mgd&tax_id=10090&chr=17&symbol=Ptprm ---------------------------------------------- ---------------------------------------------- Locus6373.htm ADDITIONAL_LINKS: key is OMIM 604852 url = http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=604852 ---------------------------------------------- key is UniGene Hs.103982 url = http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=103982 ---------------------------------------------- GeneCards url = http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?SCYB11 ---------------------------------------------- ---------------------------------------------- EXTERNAL_ANNOTATION: Not Available FUNCTION: key is GeneRIF Gene References into Function: ---------------------------------------------- 11559369 url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=11559369 chemotactic activity for CXCR3-expressing cells; substrate for dipeptidylpeptidase IV ---------------------------------------------- Gene Ontology url = http://www.geneontology.org/ ---------------------------------------------- key is Other Ontologies ---------------------------------------------- Response to injury NR Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- Anti-pathogen response NR Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- Cell migration/motility NR Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- Cell-to-cell signalling NR Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- ---------------------------------------------- key is TM ---------------------------------------------- chemokine url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0008009 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- chemotaxis url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0006935 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- signal transduction url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0007165 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- cell-cell signalling url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0007267 E Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- inflammatory response url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0006954 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- response to pathogenic fungi url = http://godatabase.org/cgi-bin/go.cgi?view=details&depth=1&query=GO:0009621 P Proteome pm url = http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&doptcmdl=DocSum&list_uids=10233762 ---------------------------------------------- ---------------------------------------------- GENBANK: A82120 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=6731985&db=Nucleotide&dopt=GenBank g CAB69205 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=6731986&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=6731986&all=1 ---------------------------------------------- AF053972 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3746491&db=Nucleotide&dopt=GenBank g AAD10206 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3746492&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=3746492&all=1 ---------------------------------------------- AF077867 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5051637&db=Nucleotide&dopt=GenBank g AAD38327 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5051638&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=5051638&all=1 ---------------------------------------------- Y15221 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5689773&db=Nucleotide&dopt=GenBank g CAB51859 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5689774&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=5689774&all=1 ---------------------------------------------- AF002985 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2580585&db=Nucleotide&dopt=GenBank m AAC51845 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=2580586&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=2580586&all=1 ---------------------------------------------- AF030514 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3219692&db=Nucleotide&dopt=GenBank m AAC39775 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=3219693&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=3219693&all=1 ---------------------------------------------- BC005292 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=13529004&db=Nucleotide&dopt=GenBank m AAH05292 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=13529005&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=13529005&all=1 ---------------------------------------------- U59286 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=1628562&db=Nucleotide&dopt=GenBank m AAB17374 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=1628563&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=1628563&all=1 ---------------------------------------------- U66096 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5058994&db=Nucleotide&dopt=GenBank m AAD38867 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=5058995&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=5058995&all=1 ---------------------------------------------- Y15220 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4225953&db=Nucleotide&dopt=GenBank m CAA75510 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4225954&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=4225954&all=1 ---------------------------------------------- ---------------------------------------------- LOCUS: Not Available MAP: key is Chromosome 4 mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&chr=4&ovr=ideogr&maps=scan-r,est,loc&VERBOSE=ON&cmd=focus&fill=40&size=40&query=SCYB11 ---------------------------------------------- key is Cytogenetic 4q21.2 RefSeq ---------------------------------------------- NOMENCLATURE: key is LocusID 6373 ---------------------------------------------- key is SCYB11 small inducible cytokine subfamily B (Cys-X-Cys), member 11 ---------------------------------------------- OVERVIEW: key is Alias small inducible cytokine subfamily B (Cys-X-Cys), member 9B ---------------------------------------------- key is Alternate Symbols IP9, B-R1, H174, IP-9, I-TAC, CXCL11, SCYB9B ---------------------------------------------- key is Locus Type gene with protein product, function known or inferred ---------------------------------------------- key is Product small inducible cytokine subfamily B (Cys-X-Cys), member 11 precursor ---------------------------------------------- key is Proteome Summary Cytokine B11; CXC chemokine that has chemotactic activity on activated T cells ---------------------------------------------- key is RefSeqSummary Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. Small inducible cytokine subfamily B member 11 (SCYB11) is a CXC member of the chemokine superfamily. It induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding SCYB11 protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of SCYB11 gene transcription. ---------------------------------------------- REFSEQ: key is REVIEWED key is Domains Small cytokines (intecrine/chemokine) url = /Structure/cdd/cddsrv.cgi?uid=pfam00048 score:76 ---------------------------------------------- Intercrine alpha family (small cytokine C-X-C) (chemokine CXC). url = /Structure/cdd/cddsrv.cgi?uid=smart00199 score:88 ---------------------------------------------- ---------------------------------------------- key is GenBank Source AF030514,U66096,Y15220 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=AF030514,U66096,Y15220&dopt=DocSum&dispmax=1000 ---------------------------------------------- key is Protein NP_005400 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=4885589&db=Protein&dopt=GenPept small inducible cytokine subfamily B (Cys-X-Cys), member 11 precursor BL url = /cgi-bin/Entrez/blink?pid=4885589&all=1 ---------------------------------------------- key is mRNA NM_005409 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=14790145&db=Nucleotide&dopt=GenBank ---------------------------------------------- key is NCBI Genome Annotation key is Annotated transcripts/proteins for this locus ---------------------------------------------- key is Domains Small cytokines (intecrine/chemokine), interleukin-8 like url = /Structure/cdd/cddsrv.cgi?uid=pfam00048 score:87 ---------------------------------------------- Intercrine alpha family (small cytokine C-X-C) (chemokine CXC). url = /Structure/cdd/cddsrv.cgi?uid=smart00199 score:89 ---------------------------------------------- ---------------------------------------------- key is Evidence supported by alignment with mRNA ---------------------------------------------- key is Genomic Contig NT_022760 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=NT_022760.10&db=Nucleotide&dopt=GenBank gb url = http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NT_022760.10&from=2657918&to=2660426&strand=1&text=on&view=genbank sv url = /entrez/viewer.cgi?val=NT_022760.10&_gene=SCYB11&view=graph mv url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/maps.cgi?ORG=hum&MAPS=est,clone,loc,cntg-r&verbose=on&gnl=NT_022760.10&query=NT_022760.10&cmd=FOCUS ev url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/evv.cgi?org=hs&contig=NT_022760.10&gene=SCYB11&lid=6373 mm url = http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/modelmaker.cgi?contig=NT_022760.10&gene=SCYB11&lid=6373 ---------------------------------------------- key is Model Protein XP_113426 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=20469054&db=Protein&dopt=GenPept BL url = /cgi-bin/Entrez/blink?pid=20469054&all=1 ---------------------------------------------- key is Model mRNA XM_113426 url = http://www.ncbi.nlm.nih.gov/entrez/viewer.cgi?val=20469053&db=Nucleotide&dopt=GenBank ---------------------------------------------- ---------------------------------------------- RELATIONSHIPS: key is Mouse Homology Maps NCBI vs. MGD Scyb11 url = ./LocRpt.cgi?l=56066 Hs url = /Homology/view.cgi?map=ncbi_mgd&tax_id=9606&chr=4&symbol=SCYB11 ---------------------------------------------- UCSC vs. MGD Scyb11 url = ./LocRpt.cgi?l=56066 Hs url = /Homology/view.cgi?map=ucsc_mgd&tax_id=9606&chr=4&symbol=SCYB11 ---------------------------------------------- ----------------------------------------------