test_locuslink Testing Bio.LocusLink on LL_block record 0 ACCNUM: ACCNUM: AC010642|9929687|na|43581|41119 TYPE: g ACCNUM: AA484435|2213248|na|na|na TYPE: m ACCNUM: AF414429|15778555|na|na|na PROT: AAL07469|15778556 TYPE: m ACCNUM: AI022193|3239546|na|na|na TYPE: m ACCNUM: AK055885|16550723|na|na|na TYPE: m ACCNUM: AK056201|16551539|na|na|na TYPE: m ACCNUM: T80683|703568|na|na|na TYPE: m ACCNUM: W25099|1302954|na|na|na TYPE: m ALIAS_SYMBOL: A1B ABG GAB ASSEMBLY: AF414429,AK055885,AK056201 CDD: Immunoglobulin C-2 Type|smart00408|104|na|4.466900e+01 Immunoglobulin C-2 Type|smart00408|104|6.130e-06|44.669 CHR: 19 COMP: 10090|A1bg|na|na|117586|19|A1BG|ncbi_mgd 10090|A1bg|7|7 cM|117586|19|A1BG|ncbi_mgd CONTIG: NT_011104.11|20544099|na|1555258|1566315|+|19 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A1BG EVID: supported by alignment with mRNA LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=373554 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=1 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=1[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:119638 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_130786 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_130786 LOCUSID: 1 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 19q13.4|RefSeq|C| MAPLINK: default_human_gene|A1BG NM: NM_130786|21071029|na NP: NP_570602|21071030 OFFICIAL_GENE_NAME: alpha-1-B glycoprotein OFFICIAL_SYMBOL: A1BG OMIM: 138670 ORGANISM: Homo sapiens PMID: 8889549,3458201,2591067 PREFERRED_PRODUCT: alpha 1B-glycoprotein PRODUCT: alpha 1B-glycoprotein STATUS: REVIEWED STS: RH65092|-|10673|na|na|epcr WI-16009|-|52209|na|na|epcr G59506|-|136670|na|na|epcr SUMMARY: Summary: The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. UNIGENE: Hs.373554 XM: XM_058938|20544041|na XP: XP_058938|17482319|na record 1 ACCNUM: ACCNUM: X68728|450521|na|na|na PROT: CAA48670|825615 TYPE: g ACCNUM: Z11711|24760|na|na|na PROT: CAA77774|24761 TYPE: g ACCNUM: M11313|177869|na|na|na PROT: AAA51551|177870 TYPE: m ACCNUM: M36501|177871|na|na|na PROT: AAA51552|177872 TYPE: m ASSEMBLY: M11313 CDD: Ependymins|EPEND|86|na|3.773540e+01 Alpha-2-macroglobulin family|pfam00207|2501|na|9.679920e+02 Alpha-2-macroglobulin family N-terminal region|pfam01835|1889|na|7.322500e+02 Alpha-2-macroglobulin family|pfam00207|2449|0.000e+00|947.962 Alpha-2-macroglobulin family N-terminal region|pfam01835|1931|0.000e+00|748.429 CHR: 12 COMP: 10090|A2m|6|6 62.00 cM|11287|12|A2M|ncbi_mgd 10090|A2m|6|6 62.00 cM|11287|12|A2M|ucsc_mgd CONTIG: NT_009702.9|20554950|na|365512|413776|+|12 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A2M EVID: supported by alignment with mRNA EXTANNOT: organismal role|CNS-specific functions|NR|Proteome|1281457 biochemical function|Inhibitor or repressor|NR|Proteome|1281457 GO: molecular function|protein carrier|NR|GO:0008320|Proteome|na molecular function|proteinase inhibitor|NR|GO:0004866|Proteome|na biological process|intracellular protein traffic|NR|GO:0006886|Proteome|na GRIF: 11811950|Differential binding to ldl receptor related protein 11823454|distinct binding sites mediate interaction with beta-amyloid peptide and growth factors LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=74561 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=2 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=2[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:119639 http://www.uwcm.ac.uk/uwcm/mg/search/119639.html http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000014 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000014 LOCUSID: 2 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 12p13.3-p12.3|HUGO|C| MAPLINK: default_human_gene|A2M NM: NM_000014|6226959|na NP: NP_000005|4557225 OFFICIAL_GENE_NAME: alpha-2-macroglobulin OFFICIAL_SYMBOL: A2M OMIM: 103950 ORGANISM: Homo sapiens PHENOTYPE: PHENOTYPE: Alzheimer disease, susceptibility to PHENOTYPE_ID: 103950 PHENOTYPE: Emphysema due to alpha-2-macroglobulin deficiency PHENOTYPE_ID: 103950 PMID: 11823454,11811950,2581245,2408344,1707161,1370808,1281457 PREFERRED_PRODUCT: alpha 2 macroglobulin precursor PRODUCT: alpha 2 macroglobulin precursor STATUS: REVIEWED STS: SGC31674|12|40245|na|na|epcr RH11157|12|46849|na|na|epcr G44356|12|95143|na|seq_map|epcr SUMFUNC: Alpha-2-macroglobulin; protease inhibitor, binds/aids in cellular internalization of proteins|Proteome SUMMARY: Summary: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. UNIGENE: Hs.74561 XM: XM_006925|18580498|na XP: XP_006925|17455493|na record 2 ACCNUM: ACCNUM: M24415|187575|na|177|2881 TYPE: g CHR: 12 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?A2MP LINK: http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:128103 LOCUSID: 3 LOCUS_CONFIRMED: yes LOCUS_TYPE: pseudogene MAP: 12p13.3-p12.3|HUGO|C| MAPLINK: default_human_cyto|A2MP OFFICIAL_GENE_NAME: alpha-2-macroglobulin pseudogene OFFICIAL_SYMBOL: A2MP ORGANISM: Homo sapiens PMID: 2478422 STATUS: REVIEWED record 3 CHR: 11 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AA LINK: http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:568984 LOCUSID: 8 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 11p15|HUGO|C| MAPLINK: default_human_cyto|AA OFFICIAL_GENE_NAME: atrophia areata, peripapillary chorioretinal degeneration OFFICIAL_SYMBOL: AA OMIM: 108985 ORGANISM: Homo sapiens PHENOTYPE: PHENOTYPE: Atrophia areata PHENOTYPE_ID: 108985 PMID: 7795606 record 4 ACCNUM: ACCNUM: AF008204|2618821|na|na|na PROT: AAB84384|2258431 TYPE: g ACCNUM: AF032677|2641552|na|na|na PROT: AAB86878|2641553 TYPE: g ACCNUM: AF032678|2641554|na|na|na PROT: AAB86879|2641555 TYPE: g ACCNUM: AF067408|3265061|na|na|na PROT: AAC24707|3265062 TYPE: g ACCNUM: AF071552|3265151|na|na|na PROT: AAC24712|3265152 TYPE: g ACCNUM: AF082903|3435297|na|na|na PROT: AAD13343|3435298 TYPE: g ACCNUM: AF082904|3435299|na|na|na PROT: AAC32388|3435300 TYPE: g ACCNUM: U80835|2245375|na|na|na PROT: AAB62398|2245376 TYPE: g ACCNUM: X17059|34993|na|na|na PROT: CAA34905|34994 TYPE: g ACCNUM: BC013732|16975545|na|na|na PROT: AAH13732|16975546 TYPE: m ACCNUM: D90041|219413|na|na|na PROT: BAA14095|219414 TYPE: m ALIAS_PROT: arylamine N-acetyltransferase-1 arylamide acetylase 1 (N-acetyltransferase 1) ALIAS_SYMBOL: AAC1 ASSEMBLY: BC013732 CDD: N-acetyltransferase|pfam00797|1030|na|4.056250e+02 CHR: 8 COMP: 10090|Nat1|8|8 31.00 cM|17960|8|NAT1|ncbi_mgd 10090|Nat1|8|8 31.00 cM|17960|8|NAT1|ucsc_mgd 10090|U35886|8|8 14135.38 cR|17961|8|AW390667|natgen_paper CONTIG: NT_030737.3|20541522|na|1907807|1921012|+|8 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?NAT1 DB_DESCR: Arylamine N-Acetyltransferase Nomenclature DB_LINK: http://www.louisville.edu/medschool/pharmacology/NAT.html ECNUM: 2.3.1.5 EVID: supported by alignment with mRNA EXTANNOT: cellular role|Other metabolism|E|Proteome|10908296 biochemical function|Transferase|E|Proteome|10908296 GO: molecular function|arylamine N-acetyltransferase|E|GO:0004060|Proteome|10908296 GRIF: 11955676|paclitaxel is an uncompetitive inhibitor to arylamine N-acetyltransferase (NAT) enzyme 11955677|paclitaxel affected human leukemia HL-60 cells arylamine N-acetyltransferase (NAT) activity and DNA-2-aminofluorene adduct formation. LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=155956 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=9 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=9[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125364 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000662 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000662 LOCUSID: 9 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 8p23.1-p21.3|HUGO|C| MAPLINK: default_human_gene|NAT1 NM: NM_000662|21361196|na NP: NP_000653|4505335 OFFICIAL_GENE_NAME: N-acetyltransferase 1 (arylamine N-acetyltransferase) OFFICIAL_SYMBOL: NAT1 OMIM: 108345 ORGANISM: Homo sapiens PMID: 11955677,11955676,10908296,10862520,9168895,7773298,2340091 PREFERRED_PRODUCT: N-acetyltransferase 1 PRODUCT: N-acetyltransferase 1 STATUS: PROVISIONAL STS: STS-D90041|8|57372|na|seq_map|epcr RH70671|8|63787|na|seq_map|epcr SUMFUNC: Arylamine N-acetyltransferase 1; N- or O-acetylates arylamines and heterocyclic amines, detoxifies carcinogens and xenobiotics|Proteome UNIGENE: Hs.155956 XM: NM_000662|21361196|na XP: NP_000653|4505335|na record 5 ACCNUM: ACCNUM: AF042740|2801806|na|na|na PROT: AAC03773|2801807 TYPE: g ACCNUM: AF055874|3063613|na|na|na PROT: AAC14117|3063614 TYPE: g ACCNUM: AF055875|3063615|na|na|na PROT: AAC14118|3063616 TYPE: g ACCNUM: D10870|219871|na|na|na PROT: BAA01640|219872 TYPE: g ACCNUM: D10871|219874|na|na|na PROT: BAA01641|219875 TYPE: g ACCNUM: D10872|219877|na|na|na PROT: BAA01642|219878 TYPE: g ACCNUM: M75163|189075|na|na|na PROT: AAA59906|553602 TYPE: g ACCNUM: M75164|189072|na|na|na PROT: AAA59905|553601 TYPE: g ACCNUM: U23052|747646|na|na|na PROT: AAA64584|727413 TYPE: g ACCNUM: U23434|727456|na|na|na PROT: AAA64585|727457 TYPE: g ACCNUM: U53473|1297331|na|na|na PROT: AAA98976|1297332 TYPE: g ACCNUM: X14672|28227|na|na|na PROT: CAA32802|28228 TYPE: g ACCNUM: BC015878|16198419|na|na|na PROT: AAH15878|16198420 TYPE: m ACCNUM: D90040|219411|na|na|na PROT: BAA14094|219412 TYPE: m ACCNUM: D90042|219415|na|na|na PROT: BAA14096|219416 TYPE: m ALIAS_PROT: Arylamine N-acetyltransferase-2 arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation) ALIAS_SYMBOL: AAC2 ASSEMBLY: D90042 CDD: N-acetyltransferase|pfam00797|838|na|3.274050e+02 CHR: 8 COMP: 10090|Nat2|8|8 31.00 cM|17961|8|NAT2|ncbi_mgd 10090|Nat2|8|8 31.00 cM|17961|8|NAT2|ucsc_mgd CONTIG: NT_030737.3|20541522|na|2088970|2098897|+|8 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?NAT2 DB_DESCR: Arylamine N-Acetyltransferase Nomenclature DB_LINK: http://www.louisville.edu/medschool/pharmacology/NAT.html ECNUM: 2.3.1.5 EVID: supported by alignment with mRNA EXTANNOT: cellular role|Other metabolism|E|Proteome|2340091 biochemical function|Transferase|E|Proteome|2340091 GO: molecular function|arylamine N-acetyltransferase|E|GO:0004060|Proteome|2340091 GRIF: 11846845|Association between bone loss in periodontal disease and polymorphism of N-acetyltransferase (NAT2) 11915035|Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. 12016157|urinary excretion of N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine relationship to activity levels of NAT2 11872636|we investigated the relationship between the levels of aromatic DNA adducts in breast tissues and polymorphisms of the drug-metabolizing genes CYP1A1, NAT2, and GSTM1 in 166 women having breast cancer LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=2 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=10 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=10[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:125365 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_000015 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_000015 http://mgc.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=2 LOCUSID: 10 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 8p22|HUGO|C| MAPLINK: default_human_gene|NAT2 NM: NM_000015|4557782|na NP: NP_000006|4557783 OFFICIAL_GENE_NAME: N-acetyltransferase 2 (arylamine N-acetyltransferase) OFFICIAL_SYMBOL: NAT2 OMIM: 243400 ORGANISM: Homo sapiens PMID: 12016157,11915035,11872636,11846845,8460648,8102597,7915226,7773298,2734109,2340091,1968463,1676262,1381364,1306121 PREFERRED_PRODUCT: arylamide acetylase 2 PRODUCT: arylamide acetylase 2 STATUS: REVIEWED STS: G06461|8|17088|na|seq_map|epcr WIAF-2120|8|44576|na|seq_map|epcr G59899|8|137181|na|seq_map|epcr GDB:187676|8|155563|na|seq_map|epcr GDB:310612|8|156422|na|seq_map|epcr GDB:310613|8|156423|na|seq_map|epcr GDB:386004|8|157141|na|seq_map|epcr SUMFUNC: Arylamine N-acetyltransferase 2; N- or O-acetylates arylamines and heterocyclic amines|Proteome SUMMARY: Summary: The intronless NAT2 gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2. UNIGENE: Hs.2 XM: NM_000015|4557782|na XP: NP_000006|4557783|na record 6 ALIAS_SYMBOL: NATP DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AACP LINK: http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:132838 LOCUSID: 11 LOCUS_CONFIRMED: yes LOCUS_TYPE: pseudogene OFFICIAL_GENE_NAME: arylamide acetylase pseudogene OFFICIAL_SYMBOL: AACP ORGANISM: Homo sapiens PMID: 2340091 record 7 ACCNUM: ACCNUM: X00947|28331|na|na|na PROT: CAA25459|28332 TYPE: g ACCNUM: X68733|439137|na|na|na PROT: CAA48671|1340142 TYPE: g ACCNUM: AF089747|4165889|na|na|na PROT: AAD08810|4165890 TYPE: m ACCNUM: BC003559|13097704|na|na|na PROT: AAH03559|13097705 TYPE: m ACCNUM: J05176|177932|na|na|na PROT: AAA51560|177933 TYPE: m ACCNUM: K01500|177808|na|na|na PROT: AAA51543|177809 TYPE: m ACCNUM: M18906|177928|na|na|na PROT: AAA51559|177931 TYPE: m ALIAS_PROT: actichymotrypsin alpha-1-antichymotrypsin ALIAS_SYMBOL: ACT AACT ASSEMBLY: AH002551,K01500 CDD: SERine Proteinase INhibitors|SERPIN|950|na|3.744620e+02 Serpins (serine protease inhibitors)|pfam00079|932|na|3.674510e+02 Serpin (S protease inhibitor)|pfam00079|1225|5.273e-136|476.478 SERine Proteinase INhibitors|smart00093|1168|2.146e-129|454.521 CHR: 14 COMP: 10090|Pre2|12|12 52.00 cM|109636|14|SERPINA3|ucsc_mgd 10090|X69832|12|12 957.87 cR|20717|14|AV689358|ucsc_est 10090|AI194247|16|16 509.87 cR|16423|14|AW819120|ucsc_est CONTIG: NT_026437.7|20543860|na|28765484|28777145|+|14 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?SERPINA3 EVID: supported by alignment with mRNA EXTANNOT: biochemical function|Inhibitor or repressor|NR|Proteome|2404007 GO: molecular function|plasma protein|NR|GO:0005209|Proteome|na biological process|acute-phase response|NR|GO:0006953|Proteome|na molecular function|proteinase inhibitor|NR|GO:0004866|Proteome|na molecular function|serine protease inhibitor|E|GO:0004867|Proteome|2404007 GRIF: 11959399|significantly higher in plasma of Alzheimer patients compared to controls 11798857|A25G and G39A substitutions in the AACT gene are probably one of the risk factors to Alzheimer's disease (AD) in Han Chinese. LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=234726 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=12 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=12[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:118955 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001085 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001085 http://mgc.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=234726 LOCUSID: 12 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 14q32.1|HUGO|C| MAPLINK: default_human_gene|SERPINA3 NM: NM_001085|9665246|na NP: NP_001076|4501843 OFFICIAL_GENE_NAME: serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 OFFICIAL_SYMBOL: SERPINA3 OMIM: 107280 ORGANISM: Homo sapiens PHENOTYPE: PHENOTYPE: Alpha-1-antichymotrypsin deficiency PHENOTYPE_ID: 107280 PHENOTYPE: Cerebrovascular disease, occlusive PHENOTYPE_ID: 107280 PMID: 11959399,11798857,9880565,8244391,6687683,6606438,6556193,6547997,3492865,3485824,3260956,3257719,2404007,1351206 PREFERRED_PRODUCT: alpha-1-antichymotrypsin, precursor PRODUCT: alpha-1-antichymotrypsin, precursor STATUS: REVIEWED STS: RH1625|14|32177|na|seq_map|epcr SHGC-32982|14|37467|na|na|epcr D14S845|14|64155|D14S845|seq_map|epcr G31126|14|66238|na|seq_map|epcr RH78280|14|74665|na|seq_map|epcr RH91507|14|86678|na|seq_map|epcr D14S1143|-|148321|D14S1143|na|epcr SUMFUNC: Alpha-1-antichymotrypsin; member of the serpin family of serine protease inhibitors|Proteome SUMMARY: Summary: The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. UNIGENE: Hs.234726 XM: XM_028322|14748211|na XP: XP_028322|14748212|na record 8 ACCNUM: ACCNUM: L32179|537513|na|na|na PROT: AAA35551|537514 TYPE: m ALIAS_SYMBOL: DAC ASSEMBLY: L32179 CDD: Carboxylesterases|pfam00135|154|na|6.439850e+01 Carboxylesterase|pfam00135|137|7.185e-10|57.381 CHR: 3 COMP: 10090|Aadac|3|3 cM|67758|3|AADAC|ncbi_mgd 10090|AI265437|3|3 5067.00 cR|67758|3|AA702448|natgen_paper CONTIG: NT_005849.11|20537660|na|726090|740503|+|3 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AADAC DB_DESCR: KEGG pathway: Butanoate metabolism DB_LINK: http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00650 DB_DESCR: KEGG pathway: 2,4-Dichlorobenzoate degradation DB_LINK: http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00623 DB_DESCR: KEGG pathway: Pentose and glucuronate interconversions DB_LINK: http://www.genome.ad.jp/dbget-bin/get_pathway?org_name=hsa&mapno=00040 ECNUM: 3.1.1.- EVID: supported by alignment with mRNA EXTANNOT: cellular role|Other metabolism|P|Proteome|8063807 subcellular localization|Microsomal fraction|NR|Proteome|8063807 GO: molecular function|enzyme|P|GO:0003824|Proteome|8063807 cellular component|microsome|E|GO:0005792|Proteome|8063807 LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=587 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=13 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=13[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:392587 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001086 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001086 LOCUSID: 13 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 3q21.3-q25.2|RefSeq|C| MAPLINK: default_human_gene|AADAC NM: NM_001086|4557226|na NP: NP_001077|4557227 OFFICIAL_GENE_NAME: arylacetamide deacetylase (esterase) OFFICIAL_SYMBOL: AADAC OMIM: 600338 ORGANISM: Homo sapiens PMID: 9299245,8063807 PREFERRED_PRODUCT: arylacetamide deacetylase PRODUCT: arylacetamide deacetylase STATUS: REVIEWED STS: STS-L32179|3|13170|na|seq_map|epcr D3S4189|-|18863|D3S4189|na|epcr RH36344|3|24707|na|seq_map|epcr RH124029|-|136046|na|na|epcr SUMFUNC: Liver microsomal arylacetamide deacetylase; esterase involved in metabolically activating arylamine carcinogens|Proteome SUMMARY: Summary: Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens UNIGENE: Hs.587 XM: XM_003002|12729778|na XP: XP_003002|11433103|na record 9 ACCNUM: ACCNUM: BC020244|18044383|na|na|na PROT: AAH20244|18044384 TYPE: m ACCNUM: M95627|870802|na|na|na PROT: AAA68889|870803 TYPE: m ASSEMBLY: M95627 CDD: WD40 repeats|smart00320|97|na|4.197260e+01 WD domain, G-beta repeat|pfam00400|90|na|3.927620e+01 CHR: 2 CONTIG: NT_005403.9|20537925|na|9668494|9674501|+|2 DB: DB_DESCR: GeneCards DB_LINK: http://bioinformatics.weizmann.ac.il/cards-bin/carddisp?AAMP EVID: supported by alignment with both mRNA and ESTs (3) EXTANNOT: organismal role|Cell migration/motility|P|Proteome|7743515 biochemical function|Adhesin/agglutinin|NR|Proteome|7743515 GO: biological process|cell motility|NR|GO:0006928|Proteome|na molecular function|heparin binding|P|GO:0008201|Proteome|7743515 LINK: http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=83347 http://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?locusId=14 http://www.ncbi.nlm.nih.gov/HomoloGene/homolquery.cgi?TEXT=14[loc] http://gdbwww.gdb.org/gdb-bin/genera/accno?GDB:4573993 http://www.ensembl.org/Homo_sapiens/contigview?geneid=NM_001087 http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg12&position=NM_001087 LOCUSID: 14 LOCUS_CONFIRMED: yes LOCUS_TYPE: gene with protein product, function known or inferred MAP: 2q36.1|RefSeq|C| MAPLINK: default_human_gene|AAMP NM: NM_001087|4557228|na NP: NP_001078|4557229 OFFICIAL_GENE_NAME: angio-associated, migratory cell protein OFFICIAL_SYMBOL: AAMP OMIM: 603488 ORGANISM: Homo sapiens PMID: 7743515 PREFERRED_PRODUCT: angio-associated, migratory cell protein PRODUCT: angio-associated, migratory cell protein STATUS: REVIEWED STS: SGC31591|2|52581|na|seq_map|epcr SUMFUNC: immunoglobulin-type protein; may mediate heparin-sensitive cell adhesion, may act in cell migration|Proteome SUMMARY: Summary: The gene product is an immunoglobulin-type protein. It is found to be expressed strongly in endothelial cells, cytotrophoblasts, and poorly differentiated colon adenocarcinoma cells found in lymphatics. The protein contains a heparin-binding domain and mediates heparin-sensitive cell adhesion. UNIGENE: Hs.83347 XM: NM_001087|4557228|na XP: NP_001078|4557229|na