Linux/Unix installation instructions follow.

To install pysoulseek from the source tree run the following:

python setup.py install --prefix=<dir>

If you omit --prefix, pysoulseek will be installed into the Python system 
directory (typically /usr).

However I do not recommend doing this as there's no way to automatically 
uninstall or properly upgrade an existing installation that was done this 
way. 

What I do recommend is doing one of these:

a) running pysoulseek right from the source distribution (.tar.gz unpacked)
by issuing this command from the command line:

python ./pyslsk

b) getting src.rpm, building binary rpm from it and installing the binary rpm.
Building a binary rpm is done by issuing 

rpmbuild --rebuild pyslsk-x.y.z.src.rpm

as root from the command line (replace x y and z with version numbers).
The build process tells you where to find the binary rpm (typically,
/usr/src/redhat/RPMS/noarch/), which you can then install as usual.

c) getting and installing a binary rpm (note: it is built with Python 2.2,
so if you have any other version of python, this binary rpm won't work).

d) It is also possible to build source and binary RPMs right from the source
distribution by running:

python setup.py bdist_rpm

You will then find source and binary RPMs in the dist directory of the source 
tree.

Note: to build source distribution (.tar.gz) from itself, run:

python setup.py sdist