#include #include #include "nifti1_io.h" #include "nifti1_local.h" /* Our local definitions */ void test_xform(mat44 m, int i, int j, int k) { double x, y, z; x = m.m[DIM_X][DIM_I] * i + m.m[DIM_X][DIM_J] * j + m.m[DIM_X][DIM_K] * k + m.m[DIM_X][3]; y = m.m[DIM_Y][DIM_I] * i + m.m[DIM_Y][DIM_J] * j + m.m[DIM_Y][DIM_K] * k + m.m[DIM_Y][3]; z = m.m[DIM_Z][DIM_I] * i + m.m[DIM_Z][DIM_J] * j + m.m[DIM_Z][DIM_K] * k + m.m[DIM_Z][3]; printf("%d %d %d => ", i, j, k); printf("%f %f %f\n", x, y, z); } static int usage(void) { static const char msg[] = { "mnc2nii: Convert MINC files to NIfTI-1 format\n" "usage: mnc2nii [-q] [filetype] [datatype] filename.mnc [filename.nii]\n" }; fprintf(stderr, "%s", msg); return (-1); } /* Explicitly set all of the fields of the NIfTI I/O header structure to * something reasonable. Right now this is overkill since a simple memset() * would do the same job, but I want this function to help me keep track * of all of the header fields and to allow me to easily override a default * if it becomes useful. */ void init_nifti_header(nifti_image *nii_ptr) { int i, j; nii_ptr->ndim = 0; nii_ptr->nx = nii_ptr->ny = nii_ptr->nz = nii_ptr->nt = nii_ptr->nu = nii_ptr->nv = nii_ptr->nw = 0; for (i = 0; i < MAX_NII_DIMS; i++) { nii_ptr->dim[i] = 0; } nii_ptr->nvox = 0; nii_ptr->nbyper = 0; nii_ptr->datatype = DT_UNKNOWN; nii_ptr->dx = nii_ptr->dy = nii_ptr->dz = nii_ptr->dt = nii_ptr->du = nii_ptr->dv = nii_ptr->dw = 0.0; for (i = 0; i < MAX_NII_DIMS; i++) { nii_ptr->pixdim[i] = 0.0; } nii_ptr->scl_slope = 0.0; nii_ptr->scl_inter = 0.0; nii_ptr->cal_min = 0.0; nii_ptr->cal_max = 0.0; nii_ptr->qform_code = NIFTI_XFORM_UNKNOWN; nii_ptr->sform_code = NIFTI_XFORM_UNKNOWN; nii_ptr->freq_dim = 0; nii_ptr->phase_dim = 0; nii_ptr->slice_dim = 0; nii_ptr->slice_code = 0; nii_ptr->slice_start = 0; nii_ptr->slice_end = 0; nii_ptr->slice_duration = 0.0; nii_ptr->quatern_b = 0.0; nii_ptr->quatern_c = 0.0; nii_ptr->quatern_d = 0.0; nii_ptr->qoffset_x = 0.0; nii_ptr->qoffset_y = 0.0; nii_ptr->qoffset_z = 0.0; nii_ptr->qfac = 0.0; nii_ptr->toffset = 0.0; nii_ptr->xyz_units = NIFTI_UNITS_MM; /* Default spatial units */ nii_ptr->time_units = NIFTI_UNITS_SEC; /* Default time units */ nii_ptr->nifti_type = FT_ANALYZE; nii_ptr->intent_code = 0; nii_ptr->intent_p1 = 0.0; nii_ptr->intent_p2 = 0.0; nii_ptr->intent_p3 = 0.0; memset(nii_ptr->intent_name, 0, sizeof (nii_ptr->intent_name)); memset(nii_ptr->descrip, 0, sizeof (nii_ptr->descrip)); memset(nii_ptr->aux_file, 0, sizeof (nii_ptr->aux_file)); nii_ptr->fname = NULL; nii_ptr->iname = NULL; nii_ptr->iname_offset = 0; nii_ptr->swapsize = 0; nii_ptr->byteorder = LSB_FIRST; /* Use LSB first by default. */ nii_ptr->data = NULL; for (i = 0; i < 4; i++) { for (j = 0; j < 4; j++) { nii_ptr->qto_xyz.m[i][j] = 0.0; nii_ptr->qto_ijk.m[i][j] = 0.0; nii_ptr->sto_xyz.m[i][j] = 0.0; nii_ptr->sto_ijk.m[i][j] = 0.0; } } } /* private function from from libminc2. This function is private partially because it's parameters are somewhat bizarre. It would be a good idea to rework them into a more rational and easily described form. */ extern void restructure_array(int ndims, unsigned char *array, const unsigned long *lengths_perm, int el_size, const int *map, const int *dir); int main(int argc, char **argv) { /* NIFTI stuff */ nifti_image *nii_ptr; nifti_image nii_rec; int nii_dimids[MAX_NII_DIMS]; int nii_dir[MAX_NII_DIMS]; int nii_map[MAX_NII_DIMS]; unsigned long nii_lens[MAX_NII_DIMS]; int nii_ndims; static int nifti_filetype; static int nifti_datatype; static int nifti_signed = 1; /* MINC stuff */ int mnc_fd; /* MINC file descriptor */ nc_type mnc_type; /* MINC data type as read */ int mnc_ndims; /* MINC image dimension count */ int mnc_dimids[MAX_VAR_DIMS]; /* MINC image dimension identifiers */ long mnc_dlen; /* MINC dimension length value */ double mnc_dstep; /* MINC dimension step value */ int mnc_icv; /* MINC image conversion variable */ int mnc_vid; /* MINC Image variable ID */ long mnc_start[MAX_VAR_DIMS]; /* MINC data starts */ long mnc_count[MAX_VAR_DIMS]; /* MINC data counts */ int mnc_signed; /* MINC if output voxels are signed */ double mnc_rrange[2]; /* MINC real range (min, max) */ double mnc_vrange[2]; /* MINC valid range (min, max) */ /* Other stuff */ char out_str[1024]; /* Big string for filename */ char att_str[1024]; /* Big string for attribute values */ int i; /* Generic loop counter the first */ int j; /* Generic loop counter the second */ char *str_ptr; /* Generic ASCIZ string pointer */ int r; /* Result code. */ static int qflag = 0; /* Quiet flag (default is non-quiet) */ static ArgvInfo argTable[] = { {NULL, ARGV_HELP, NULL, NULL, "Output voxel data type specification"}, {"-byte", ARGV_CONSTANT, (char *)DT_INT8, (char *)&nifti_datatype, "Write voxel data in 8-bit signed integer format."}, {"-short", ARGV_CONSTANT, (char *)DT_INT16, (char *)&nifti_datatype, "Write voxel data in 16-bit signed integer format."}, {"-int", ARGV_CONSTANT, (char *)DT_INT32, (char *)&nifti_datatype, "Write voxel data in 32-bit signed integer format."}, {"-float", ARGV_CONSTANT, (char *)DT_FLOAT32, (char *)&nifti_datatype, "Write voxel data in 32-bit floating point format."}, {"-double", ARGV_CONSTANT, (char *)DT_FLOAT64, (char *)&nifti_datatype, "Write voxel data in 64-bit floating point format."}, {"-signed", ARGV_CONSTANT, (char *)1, (char *)&nifti_signed, "Write integer voxel data in signed format."}, {"-unsigned", ARGV_CONSTANT, (char *)0, (char *)&nifti_signed, "Write integer voxel data in unsigned format."}, {NULL, ARGV_HELP, NULL, NULL, "Output file format specification"}, {"-dual", ARGV_CONSTANT, (char *)FT_NIFTI_DUAL, (char *)&nifti_filetype, "Write NIfTI-1 two-file format (.img and .hdr)"}, {"-ASCII", ARGV_CONSTANT, (char *)FT_NIFTI_ASCII, (char *)&nifti_filetype, "Write NIfTI-1 ASCII header format (.nia)"}, {"-nii", ARGV_CONSTANT, (char *)FT_NIFTI_SINGLE, (char *)&nifti_filetype, "Write NIfTI-1 one-file format (.nii)"}, {"-analyze", ARGV_CONSTANT, (char *)FT_ANALYZE, (char *)&nifti_filetype, "Write an Analyze two-file format file (.img and .hdr)"}, {NULL, ARGV_HELP, NULL, NULL, "Other options"}, {"-quiet", ARGV_CONSTANT, (char *)0, (char *)&qflag, "Quiet operation"}, {NULL, ARGV_END, NULL, NULL, NULL} }; ncopts = 0; /* Clear global netCDF error reporting flag */ /* Default NIfTI file type is "NII", single binary file */ nifti_filetype = FT_UNSPECIFIED; nifti_datatype = DT_UNKNOWN; if (ParseArgv(&argc, argv, argTable, 0) || (argc < 2)) { fprintf(stderr, "Too few arguments\n"); return usage(); } if (!nifti_signed) { switch (nifti_datatype) { case DT_INT8: nifti_datatype = DT_UINT8; break; case DT_INT16: nifti_datatype = DT_UINT16; break; case DT_INT32: nifti_datatype = DT_UINT32; break; } } switch (nifti_datatype){ case DT_INT8: case DT_UINT8: mnc_type = NC_BYTE; break; case DT_INT16: case DT_UINT16: mnc_type = NC_SHORT; break; case DT_INT32: case DT_UINT32: mnc_type = NC_INT; break; case DT_FLOAT32: mnc_type = NC_FLOAT; break; case DT_FLOAT64: mnc_type = NC_DOUBLE; break; } if (argc == 2) { strcpy(out_str, argv[1]); str_ptr = strrchr(out_str, '.'); if (str_ptr != NULL && !strcmp(str_ptr, ".mnc")) { *str_ptr = '\0'; } } else if (argc == 3) { strcpy(out_str, argv[2]); str_ptr = strrchr(out_str, '.'); if (str_ptr != NULL) { /* See if a recognized file extension was specified. If so, * we trim it off and set the output file type if none was * specified. If the extension is not recognized, assume * that we will form the filename by just adding the right * extension for the selected output format. */ if (!strcmp(str_ptr, ".nii")) { if (nifti_filetype == FT_UNSPECIFIED) { nifti_filetype = FT_NIFTI_SINGLE; } *str_ptr = '\0'; } else if (!strcmp(str_ptr, ".img") || !strcmp(str_ptr, ".hdr")) { if (nifti_filetype == FT_UNSPECIFIED) { nifti_filetype = FT_NIFTI_DUAL; } *str_ptr = '\0'; } else if (!strcmp(str_ptr, ".nia")) { if (nifti_filetype == FT_UNSPECIFIED) { nifti_filetype = FT_NIFTI_ASCII; } *str_ptr = '\0'; } } } else { fprintf(stderr, "Filename argument required\n"); return usage(); } /* Open the MINC file. It needs to exist. */ mnc_fd = miopen(argv[1], NC_NOWRITE); if (mnc_fd < 0) { fprintf(stderr, "Can't find input file '%s'\n", argv[1]); return (-1); } /* Find the MINC image variable. If we can't find it, there is no * further processing possible... */ mnc_vid = ncvarid(mnc_fd, MIimage); if (mnc_vid < 0) { fprintf(stderr, "Can't locate the image variable\n"); return (-1); } /* Find out about the MINC image variable - specifically, how many * dimensions, and which dimensions. */ r = ncvarinq(mnc_fd, mnc_vid, NULL, NULL, &mnc_ndims, mnc_dimids, NULL); if (r < 0) { fprintf(stderr, "Can't read information from image variable\n"); return (-1); } if (mnc_ndims > MAX_NII_DIMS) { fprintf(stderr, "NIfTI-1 files may contain at most %d dimensions\n", MAX_NII_DIMS); return (-1); } /* Initialize the NIfTI structure */ nii_ptr = &nii_rec; init_nifti_header(nii_ptr); /* For now we just use the mnc2nii command line as the description * field. Probably we should use something better, perhaps a * combination of some other standard MINC fields that might * provide more information. */ str_ptr = nii_ptr->descrip; for (i = 0; i < argc; i++) { char *arg_ptr = argv[i]; if ((str_ptr - nii_ptr->descrip) >= MAX_NII_DESCRIP) { break; } if (i != 0) { *str_ptr++ = ' '; } while (*arg_ptr != '\0' && (str_ptr - nii_ptr->descrip) < MAX_NII_DESCRIP) { *str_ptr++ = *arg_ptr++; } *str_ptr = '\0'; } nii_ptr->fname = malloc(strlen(out_str) + 4); nii_ptr->iname = malloc(strlen(out_str) + 4); strcpy(nii_ptr->fname, out_str); strcpy(nii_ptr->iname, out_str); switch (nifti_filetype) { case FT_ANALYZE: strcat(nii_ptr->fname, ".hdr"); strcat(nii_ptr->iname, ".img"); break; case FT_NIFTI_SINGLE: strcat(nii_ptr->fname, ".nii"); strcat(nii_ptr->iname, ".nii"); break; case FT_NIFTI_DUAL: strcat(nii_ptr->fname, ".hdr"); strcat(nii_ptr->iname, ".img"); break; case FT_NIFTI_ASCII: strcat(nii_ptr->fname, ".nia"); strcat(nii_ptr->iname, ".nia"); break; default: fprintf(stderr, "Unknown output file type %d\n", nifti_filetype); return (-1); } miget_image_range(mnc_fd, mnc_rrange); /* Get real range */ miget_valid_range(mnc_fd, mnc_vid, mnc_vrange); /* Get voxel range */ if (mnc_vrange[1] != mnc_vrange[0] && mnc_rrange[1] != mnc_rrange[0]) { nii_ptr->scl_slope = ((mnc_rrange[1] - mnc_rrange[0]) / (mnc_vrange[1] - mnc_vrange[0])); nii_ptr->scl_inter = mnc_rrange[0] - (mnc_vrange[0] * nii_ptr->scl_slope); } else { nii_ptr->scl_slope = 0.0; } nii_ptr->nvox = 1; /* Initial value for voxel count */ /* Find all of the dimensions of the MINC file, in the order they * will be listed in the NIfTI-1/Analyze file. We use this to build * a map for restructuring the data according to the normal rules * of NIfTI-1. */ nii_ndims = 0; for (i = 0; i < MAX_NII_DIMS; i++) { if (dimnames[i] == NULL) { nii_dimids[nii_ndims] = -1; continue; } nii_dimids[nii_ndims] = ncdimid(mnc_fd, dimnames[i]); if (nii_dimids[nii_ndims] == -1) { continue; } /* Make sure the dimension is actually used to define the image. */ for (j = 0; j < mnc_ndims; j++) { if (nii_dimids[nii_ndims] == mnc_dimids[j]) { nii_map[nii_ndims] = j; break; } } if (j < mnc_ndims) { mnc_dlen = 1; mnc_dstep = 0; ncdiminq(mnc_fd, nii_dimids[nii_ndims], NULL, &mnc_dlen); ncattget(mnc_fd, ncvarid(mnc_fd, dimnames[i]), MIstep, &mnc_dstep); if (mnc_dstep < 0) { nii_dir[nii_ndims] = -1; mnc_dstep = -mnc_dstep; } else { nii_dir[nii_ndims] = 1; } nii_lens[nii_ndims] = mnc_dlen; nii_ndims++; } nii_ptr->dim[dimmap[i]] = (int) mnc_dlen; nii_ptr->nvox *= mnc_dlen; nii_ptr->pixdim[dimmap[i]] = (float) mnc_dstep; } nii_ptr->ndim = nii_ndims; /* Total number of dimensions in file */ nii_ptr->nx = nii_ptr->dim[0]; nii_ptr->ny = nii_ptr->dim[1]; nii_ptr->nz = nii_ptr->dim[2]; nii_ptr->nt = nii_ptr->dim[3]; nii_ptr->nu = nii_ptr->dim[4]; nii_ptr->dx = nii_ptr->pixdim[0]; nii_ptr->dy = nii_ptr->pixdim[1]; nii_ptr->dz = nii_ptr->pixdim[2]; nii_ptr->dt = nii_ptr->pixdim[3]; nii_ptr->du = 1; /* MINC files don't define a sample size for a vector_dimension */ nii_ptr->nifti_type = nifti_filetype; if (nifti_datatype == DT_UNKNOWN) { nii_ptr->datatype = DT_FLOAT32; /* Default */ mnc_type = NC_FLOAT; mnc_signed = 1; } else { nii_ptr->datatype = nifti_datatype; } /* Load the direction_cosines and start values into the NIfTI-1 * sform structure. * */ for (i = 0; i < MAX_SPACE_DIMS; i++) { int id = ncvarid(mnc_fd, mnc_spatial_names[i]); double start; double step; double dircos[MAX_SPACE_DIMS]; int tmp; if (id < 0) { continue; } /* Set default values */ start = 0.0; step = 1.0; dircos[DIM_X] = dircos[DIM_Y] = dircos[DIM_Z] = 0.0; dircos[i] = 1.0; miattget(mnc_fd, id, MIstart, NC_DOUBLE, 1, &start, &tmp); miattget(mnc_fd, id, MIstep, NC_DOUBLE, 1, &step, &tmp); miattget(mnc_fd, id, MIdirection_cosines, NC_DOUBLE, MAX_SPACE_DIMS, dircos, &tmp); ncdiminq(mnc_fd, ncdimid(mnc_fd, mnc_spatial_names[i]), NULL, &mnc_dlen); if (step < 0) { step = -step; start = start - step * (mnc_dlen - 1); } nii_ptr->sto_xyz.m[0][i] = step * dircos[0]; nii_ptr->sto_xyz.m[1][i] = step * dircos[1]; nii_ptr->sto_xyz.m[2][i] = step * dircos[2]; nii_ptr->sto_xyz.m[0][3] += start * dircos[0]; nii_ptr->sto_xyz.m[1][3] += start * dircos[1]; nii_ptr->sto_xyz.m[2][3] += start * dircos[2]; miattgetstr(mnc_fd, id, MIspacetype, sizeof(att_str), att_str); /* Try to set the S-transform code correctly. It is unclear that * this is the right way to do it. */ if (!strcmp(att_str, MI_NATIVE)) { nii_ptr->sform_code = NIFTI_XFORM_SCANNER_ANAT; } if (!strcmp(att_str, MI_TALAIRACH)) { nii_ptr->sform_code = NIFTI_XFORM_TALAIRACH; } /* TODO: Anything for MI_CALLOSAL? */ } /* So the last row is right... */ nii_ptr->sto_xyz.m[3][0] = 0.0; nii_ptr->sto_xyz.m[3][1] = 0.0; nii_ptr->sto_xyz.m[3][2] = 0.0; nii_ptr->sto_xyz.m[3][3] = 1.0; nii_ptr->sto_ijk = mat44_inverse(nii_ptr->sto_xyz); nifti_datatype_sizes(nii_ptr->datatype, &nii_ptr->nbyper, &nii_ptr->swapsize); if (!qflag) { nifti_image_infodump(nii_ptr); } /* Now load the actual MINC data. */ nii_ptr->data = malloc(nii_ptr->nbyper * nii_ptr->nvox); if (nii_ptr->data == NULL) { fprintf(stderr, "Out of memory.\n"); return (-1); } if (!qflag) { fprintf(stderr, "MINC type %d signed %d\n", mnc_type, mnc_signed); } mnc_icv = miicv_create(); miicv_setint(mnc_icv, MI_ICV_TYPE, mnc_type); miicv_setstr(mnc_icv, MI_ICV_SIGN, (mnc_signed) ? MI_SIGNED : MI_UNSIGNED); miicv_setdbl(mnc_icv, MI_ICV_VALID_MAX, mnc_vrange[1]); miicv_setdbl(mnc_icv, MI_ICV_VALID_MIN, mnc_vrange[0]); miicv_setint(mnc_icv, MI_ICV_DO_NORM, 1); miicv_attach(mnc_icv, mnc_fd, mnc_vid); /* Read in the entire hyperslab from the file. */ for (i = 0; i < mnc_ndims; i++) { ncdiminq(mnc_fd, mnc_dimids[i], NULL, &mnc_count[i]); mnc_start[i] = 0; } r = miicv_get(mnc_icv, mnc_start, mnc_count, nii_ptr->data); if (r < 0) { fprintf(stderr, "Read error\n"); return (-1); } /* Shut down the MINC stuff now that it has done its work. */ miicv_detach(mnc_icv); miicv_free(mnc_icv); miclose(mnc_fd); if (!qflag) { /* Debugging stuff - just to check the contents of these arrays. */ for (i = 0; i < nii_ndims; i++) { printf("%d: %ld %d %d\n", i, nii_lens[i], nii_map[i], nii_dir[i]); } printf("bytes per voxel %d\n", nii_ptr->nbyper); printf("# of voxels %ld\n", nii_ptr->nvox); } /* Rearrange the data to correspond to the NIfTI dimension ordering. */ restructure_array(nii_ndims, nii_ptr->data, nii_lens, nii_ptr->nbyper, nii_map, nii_dir); if (!qflag) { /* More debugging stuff - check coordinate transform. */ test_xform(nii_ptr->sto_xyz, 0, 0, 0); test_xform(nii_ptr->sto_xyz, 10, 0, 0); test_xform(nii_ptr->sto_xyz, 0, 10, 0); test_xform(nii_ptr->sto_xyz, 0, 0, 10); test_xform(nii_ptr->sto_xyz, 10, 10, 10); } nifti_image_write(nii_ptr); return (0); }